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Urolithin A
CAS No. 1143-70-0
Urolithin A( 2',7-Dihydroxy-3,4-benzocoumarin | 3,8-Dihydroxy Urolithin )
Catalog No. M10510 CAS No. 1143-70-0
A first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption; prevents the accumulation of dysfunctional mitochondria with age and extends lifespan in C. elegans, improves exercise capacity in mouse models of age-related decline of muscle function.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 38 | In Stock |
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| 10MG | 59 | In Stock |
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| 25MG | 119 | In Stock |
|
| 50MG | 177 | In Stock |
|
| 100MG | 303 | In Stock |
|
| 200MG | 447 | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameUrolithin A
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NoteResearch use only, not for human use.
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Brief DescriptionA first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption; prevents the accumulation of dysfunctional mitochondria with age and extends lifespan in C. elegans, improves exercise capacity in mouse models of age-related decline of muscle function.
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DescriptionA first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption; prevents the accumulation of dysfunctional mitochondria with age and extends lifespan in C. elegans, improves exercise capacity in mouse models of age-related decline of muscle function.
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In Vitro——
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In Vivo——
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Synonyms2',7-Dihydroxy-3,4-benzocoumarin | 3,8-Dihydroxy Urolithin
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PathwayAutophagy
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TargetMitophagy
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RecptorMitophagy
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number1143-70-0
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Formula Weight228.2002
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Molecular FormulaC13H8O4
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 33 mg/mL
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SMILESO=C1C2=CC(O)=CC=C2C3=C(O1)C=C(O)C=C3
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Chemical Name6H-Dibenzo[b,d]pyran-6-one, 3,8-dihydroxy-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Urolithin A
A first-in-class natural compound that induces mitophagy both in vitro and in vivo following oral consumption; prevents the accumulation of dysfunctional mitochondria with age and extends lifespan in C. elegans, improves exercise capacity in mouse models of age-related decline of muscle function.
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Mtphagy Dye
Mtphagy Dye is a small-molecule fluorescent probe for visualizing mitophagy; has suitable fluorescent properties for detecting mitochondrial acidification during mitophagy in the long-wavelength region that does not damage mitochondria.
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U0126
U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively. U0126 inhibits autophagy and mitophagy.
